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m1 sinobiological 40904 v07h  (Sino Biological)


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    Sino Biological m1 sinobiological 40904 v07h
    M1 Sinobiological 40904 V07h, supplied by Sino Biological, used in various techniques. Bioz Stars score: 94/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/m1 sinobiological 40904 v07h/product/Sino Biological
    Average 94 stars, based on 18 article reviews
    m1 sinobiological 40904 v07h - by Bioz Stars, 2026-02
    94/100 stars

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    A) Study schedule with median visit times. Ranges of visit times included in each visit are in parentheses. All times are in relation to the previous vaccine dose. Image generated with BioRender. B) Neutralizing titers against clade IIb <t>MPXV</t> as measured by microneutralization assay with 5% guinea pig serum. Mpox convalescent samples are from the indicated time point post-symptom onset. Naïve and experienced controls were collected pre-2022. Black bars represent the geometric mean. Samples with ID 50 values below the limit of detection (LOD) are assigned a value of 10, or ½ the LOD. C) Spearman correlation of IgG for the indicated protein versus MPXV neutralizing titers. Samples are from V4. D) Avidity index for IgG that correlated with MPXV neutralization in both naïve and experienced vaccinees in C. Only avidity measurements from samples with above background binding are included. Black bars represent the mean. Statistics for panel B were performed using the Kruskal-Wallis test with Dunn’s method for multiple comparisons and for panel D were performed using ordinary one-way ANOVA with Šídák’s multiple comparisons test. MPXV Conv, mpox convalescent patients; IMV, intracellular mature virion; EEV, extracellular enveloped virion.
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    A) Study schedule with median visit times. Ranges of visit times included in each visit are in parentheses. All times are in relation to the previous vaccine dose. Image generated with BioRender. B) Neutralizing titers against clade IIb MPXV as measured by microneutralization assay with 5% guinea pig serum. Mpox convalescent samples are from the indicated time point post-symptom onset. Naïve and experienced controls were collected pre-2022. Black bars represent the geometric mean. Samples with ID 50 values below the limit of detection (LOD) are assigned a value of 10, or ½ the LOD. C) Spearman correlation of IgG for the indicated protein versus MPXV neutralizing titers. Samples are from V4. D) Avidity index for IgG that correlated with MPXV neutralization in both naïve and experienced vaccinees in C. Only avidity measurements from samples with above background binding are included. Black bars represent the mean. Statistics for panel B were performed using the Kruskal-Wallis test with Dunn’s method for multiple comparisons and for panel D were performed using ordinary one-way ANOVA with Šídák’s multiple comparisons test. MPXV Conv, mpox convalescent patients; IMV, intracellular mature virion; EEV, extracellular enveloped virion.

    Journal: medRxiv

    Article Title: A three-dose MVA-BN mpox vaccination series improves the quality of anti-monkeypox virus immunity

    doi: 10.1101/2025.10.31.25339252

    Figure Lengend Snippet: A) Study schedule with median visit times. Ranges of visit times included in each visit are in parentheses. All times are in relation to the previous vaccine dose. Image generated with BioRender. B) Neutralizing titers against clade IIb MPXV as measured by microneutralization assay with 5% guinea pig serum. Mpox convalescent samples are from the indicated time point post-symptom onset. Naïve and experienced controls were collected pre-2022. Black bars represent the geometric mean. Samples with ID 50 values below the limit of detection (LOD) are assigned a value of 10, or ½ the LOD. C) Spearman correlation of IgG for the indicated protein versus MPXV neutralizing titers. Samples are from V4. D) Avidity index for IgG that correlated with MPXV neutralization in both naïve and experienced vaccinees in C. Only avidity measurements from samples with above background binding are included. Black bars represent the mean. Statistics for panel B were performed using the Kruskal-Wallis test with Dunn’s method for multiple comparisons and for panel D were performed using ordinary one-way ANOVA with Šídák’s multiple comparisons test. MPXV Conv, mpox convalescent patients; IMV, intracellular mature virion; EEV, extracellular enveloped virion.

    Article Snippet: Briefly, ten different OPXV proteins were included in the panel: MPXV H3 (Sino Biological 40893-V08H1), MPXV A35 (Sino Biological 40886-V08H), MPXV A29 (Sino Biological 40891-V08E), MPXV A30 (Cell Sciences YVV15001A), MPXV M1 (Sino Biological 40904-V07H), MPXV B2 (Abbexa abx620100), MPXV A27 (Abbexa abx620105), MPXV B6 (Abbexa abx620118), VACV A33 (Sino Biological 40896-V07E), and VACV B5 (Sino Biological 40900-V08H).

    Techniques: Generated, Microneutralization Assay, Neutralization, Binding Assay

    A-D) Comparison of MPXV neutralizing titer as assayed in of Robust versus Standard Responders for V3 (A), V4 (B), V5 (C), and V6 (D). E) Comparison of IgG avidity for Robust versus Standard Responders. F) Comparison of dosing interval for Robust versus Standard Responders. Black bars on all panels represent the mean. Statistics for panels A through D and F were performed using the Mann-Whitney test and for panel E were performed using ordinary one-way ANOVA with Šídák’s multiple comparisons test.

    Journal: medRxiv

    Article Title: A three-dose MVA-BN mpox vaccination series improves the quality of anti-monkeypox virus immunity

    doi: 10.1101/2025.10.31.25339252

    Figure Lengend Snippet: A-D) Comparison of MPXV neutralizing titer as assayed in of Robust versus Standard Responders for V3 (A), V4 (B), V5 (C), and V6 (D). E) Comparison of IgG avidity for Robust versus Standard Responders. F) Comparison of dosing interval for Robust versus Standard Responders. Black bars on all panels represent the mean. Statistics for panels A through D and F were performed using the Mann-Whitney test and for panel E were performed using ordinary one-way ANOVA with Šídák’s multiple comparisons test.

    Article Snippet: Briefly, ten different OPXV proteins were included in the panel: MPXV H3 (Sino Biological 40893-V08H1), MPXV A35 (Sino Biological 40886-V08H), MPXV A29 (Sino Biological 40891-V08E), MPXV A30 (Cell Sciences YVV15001A), MPXV M1 (Sino Biological 40904-V07H), MPXV B2 (Abbexa abx620100), MPXV A27 (Abbexa abx620105), MPXV B6 (Abbexa abx620118), VACV A33 (Sino Biological 40896-V07E), and VACV B5 (Sino Biological 40900-V08H).

    Techniques: Comparison, MANN-WHITNEY

    A) MPXV neutralization as assayed in for booster subjects in . B) Comparison of peak neutralizing titers following dose two and three. C-G) Avidity index for IgG against MPXV H3 (C), MPXV M1 (D), VACV B5 (E), MPXV A35 (F), and VACV A33 (G). Avidity measurements for post-boost samples use the 1 month post-boost time point with the exception of the measurement for Booster 2 on MPXV A35, which uses the 1 week post-boost time point due to negative levels of anti-MPXV A35 binding at the 1 month time point. Measurements from are shown here for the two dose group. Black bars on panels C through G represent the mean. Statistics were performed using Wilcoxon matched-pairs signed rank test for panel B and ordinary one-way ANOVA with Holm-Šídák’s multiple comparisons test for panels C through G.

    Journal: medRxiv

    Article Title: A three-dose MVA-BN mpox vaccination series improves the quality of anti-monkeypox virus immunity

    doi: 10.1101/2025.10.31.25339252

    Figure Lengend Snippet: A) MPXV neutralization as assayed in for booster subjects in . B) Comparison of peak neutralizing titers following dose two and three. C-G) Avidity index for IgG against MPXV H3 (C), MPXV M1 (D), VACV B5 (E), MPXV A35 (F), and VACV A33 (G). Avidity measurements for post-boost samples use the 1 month post-boost time point with the exception of the measurement for Booster 2 on MPXV A35, which uses the 1 week post-boost time point due to negative levels of anti-MPXV A35 binding at the 1 month time point. Measurements from are shown here for the two dose group. Black bars on panels C through G represent the mean. Statistics were performed using Wilcoxon matched-pairs signed rank test for panel B and ordinary one-way ANOVA with Holm-Šídák’s multiple comparisons test for panels C through G.

    Article Snippet: Briefly, ten different OPXV proteins were included in the panel: MPXV H3 (Sino Biological 40893-V08H1), MPXV A35 (Sino Biological 40886-V08H), MPXV A29 (Sino Biological 40891-V08E), MPXV A30 (Cell Sciences YVV15001A), MPXV M1 (Sino Biological 40904-V07H), MPXV B2 (Abbexa abx620100), MPXV A27 (Abbexa abx620105), MPXV B6 (Abbexa abx620118), VACV A33 (Sino Biological 40896-V07E), and VACV B5 (Sino Biological 40900-V08H).

    Techniques: Neutralization, Comparison, Binding Assay

    Summary of ROC curves and MFI cutoffs for presumed negative samples (n=63) vs positive samples (n=435) to 12 MPXV and VACV antigens by ROC analysis

    Journal: The Lancet. Microbe

    Article Title: Assessment of MpoxPlex, a high-throughput and multiplexed immunoassay: a diagnostic accuracy study

    doi: 10.1016/j.lanmic.2024.100987

    Figure Lengend Snippet: Summary of ROC curves and MFI cutoffs for presumed negative samples (n=63) vs positive samples (n=435) to 12 MPXV and VACV antigens by ROC analysis

    Article Snippet: Recombinant MPXV antigens A29, A35, H3, and M1 were purchased from Sino Biological (Eschborn, Germany; product codes 40891V08E, 40886V08H, 40893V08H1, and 40904V07H).

    Techniques: